EMBRYONIC STEM CELL-DERIVED CARDIOMYOCYTE HETEROGENEITY AND THE ISOLATION OF IMMATURE AND COMMITTED CELLS FOR CARDIAC REMODELING AND REGENERATION

Embryonic Stem Cell-Derived Cardiomyocyte Heterogeneity and the Isolation of Immature and Committed Cells for Cardiac Remodeling and Regeneration

Pluripotent stem cells represent one promising source for cell replacement therapy in heart, but differentiating embryonic stem cell-derived cardiomyocytes (ESC-CMs) are highly heterogeneous and show a variety of maturation states.In this study, we employed an ESC clonal hindigyanvishv.com line that contains a cardiac-restricted ncx1 promoter-drive

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From 3D spheroids to tumor bearing mice: efficacy and distribution studies of trastuzumab-docetaxel immunoliposome in breast cancer

Anne Rodallec,1 Guillaume Sicard,1 Sarah Giacometti,1 Manon Carré,1 Bertrand Pourroy,2 Fanny Bouquet,3 Ariel Savina,3 Bruno Lacarelle,1 Joseph Ciccolini,1 Raphaelle Fanciullino1 1SMARTc Unit, Laboratory of Pharmacokinetics and Toxicology UFR Pharmacy, Center for Research on Cancer of Marseille, Inserm UMR1068, CNRS UMR7258, Aix Marseille Uni

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A comparative approach to the institutions of appeal in favor of the law and Contrary to the Sharia approach in French and Iranian criminal law

according to the article 477 of the Code of Criminal Procedure 2014(1392), the institution of retrial has been envisaged by the head of the judiciary as one of the extraordinary ways to challenge the votes, by recognizing the opposition of read more the vote to Sharia.The study of French criminal law also shows that the establishment of an appeal i

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Obtaining Sound Intraclass Correlation and Variance Estimates in Three-Level Models: The Role of Sampling-Strategies

Three-level clustered data commonly occur in social and behavioral research and are prominently analyzed using multilevel modeling.The influence of the clustering on estimation results is assessed with the intraclass correlation coefficients (ICCs), which indicate the fraction of variance in the outcome located at each higher level.However, ICCs ar

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The challenges of widening access to the medical profession: how to facilitate medical careers for those at a genuine disadvantage [Version 2]

Widening Participation (WP) for medical school entry has been politically encouraged to ensure access and participation for underrepresented groups that are rarely able to gain access to this high demand profession.Those who reside in the 20% most deprived postcodes in Scotland (SIMD20, Scottish Index of Multiple Deprivation) are much less likely t

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